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Concomitant administration of promethazine products with other respiratory depressants has an association with respiratory melancholy, and at times Demise, in pediatric individuals.
A prolonged, ten-webpage report launched two days after Gaulden’s arrest thorough many incidents in which a physician was impersonated and fraudulent prescriptions had been obtained.
Promethazine with Codeine Oral Solution contains codeine, a Schedule V managed compound. Being an opioid, Promethazine with Codeine Oral Remedy exposes consumers towards the challenges of habit, abuse, and misuse [see Drug Abuse and Dependence ( 9)], which can result in overdose and death [see Overdosage ( ten)]. Reserve Promethazine with Codeine Oral Answer to be used in adult sufferers for whom the benefits of cough suppression are expected to outweigh the challenges, and in whom an adequate evaluation in the etiology of your cough has been made. Evaluate Each and every individual’s threat prior to prescribing Promethazine with Codeine Oral Option, prescribe Promethazine with Codeine Oral Alternative to the shortest duration that is definitely according to specific patient procedure targets, check all people routinely for the event of addiction or abuse, and refill only immediately after reevaluation of the need for ongoing treatment method.
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The mixture of promethazine hydrochloride and codeine phosphate is contraindicated in pediatric sufferers fewer than six several years of age, since The mix may well cause deadly respiratory despair On this age populace (see WARNINGS – Box Warning and Use In Pediatric Sufferers).
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Some medicines can communicate with codeine and bring about a significant situation known as serotonin syndrome. Make certain your physician is familiar with if In addition, you get stimulant drugs, herbal products and solutions, or medication for despair, mental health issues, Parkinson's disorder, migraine complications, major bacterial infections, or avoidance of nausea and vomiting. Question your health practitioner before you make any alterations in how or once you just take your here drugs.
Use: For your management of mild to average soreness website where by therapy with the opioid is suitable and from which different treatment plans are insufficient.
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Excessively large dosages of antihistamines, such as promethazine hydrochloride, in pediatric clients might result in unexpected Dying (see OVERDOSAGE). Hallucinations and convulsions have happened with click here therapeutic doses and overdoses of promethazine hydrochloride in pediatric people. In pediatric patients that are acutely sick connected with dehydration, There may be a heightened susceptibility to dystonias with the usage of promethazine HCl.
The mixture of promethazine hydrochloride and codeine phosphate is contraindicated in pediatric sufferers lower than 6 decades of age, for the reason that The mixture may possibly result in deadly respiratory depression During this age populace.
In case you have any questions about promethazine and codeine, remember to talk with the physician, pharmacist, or other well being treatment service provider. If you're thinking that There's been an overdose, contact your poison control Centre or get professional medical treatment instantly. Be willing to inform or show what was taken, exactly how much, and when it took place. More about codeine / promethazine